Key Highlights :
Scientists discovered Neutralization antibodies in May 2020 and a possible indicator for treatment and diagnostic target. One of the excellent outcomes of the pandemic has been COVID-19 Neutralizing antibodies (NAbs). B cells in the human body produce these NAB.NAB’s primary function is to stop infections by eliminating the invading pathogen.
What are Neutralizing antibodies?
NAb’s from SARS-CoV-2 usually appear approximately 07-15 days post-infection. The serological tests cannot diagnose early infections but can stretch the time of the testing window beyond the acute infection phase.
These tests assist in the tracking of infection chains. NAB’s are used to answer virological and epidemiological situations. They also answer clinical questions, including, but not limited to, whether a robust antibody response has occurred and how many infected individuals have remained asymptomatic.
Among the various antibodies raised in response to infection, coronavirus NAbs are highly unique. NAb also mitigates the risk of transferral of genes to host cells by viruses.
What is the Significance of SARS-CoV-2 neutralizing antibodies?
NAb prevents the virus from spreading to healthy cells and eliminate the infection in the early stages itself.
The appearance of Neutralizing antibodies correlates with protection from viral infection. Hence, they play an essential role in SARS-CoV-2 treatment, vaccine, and research and development.
Neutralizing antibodies prevent the interaction between the virus and our cells and help eliminate the infection during its early stages. Thus, measuring the quantity of these antibodies is critical for evaluating potential SARS-CoV-2 vaccines.
NAB’s assist in specific therapies that are also being used to treat people already infected with the virus. These therapies, so far, are showing great promise in reducing hospitalizations and death.