Ferritin is a protein widely distributed across all living organisms, including bacteria, algae, higher plants, animals, and humans. Ferritin stores iron in our cells and indirectly reflects the amount of iron in our body. Iron is important for healthy red blood cells, muscles, bone marrow and organs.
Clinical Significance of Ferritin and Interpretation
Its clinical significance lies in its role in diagnosing and managing diseases, including:
• Hemochromatosis- having too much iron in your body, also called as iron overload.
• Iron deficiency, also called anaemia, is a condition in which your body has too few red blood cells.
• Liver diseases, including cirrhosis, where a high amount of ferritin is stored in the liver.
• AOSD, also called adult-onset Still disease, is an uncommon disease that causes joint pain, fever, arthritis and rash, with high ferritin levels.
• Monitoring of chronic conditions such as cancer, kidney disease, and autoimmune diseases.
• Parkinson’s disease is also linked to abnormalities in ferritin levels.
Different Diagnostic ways to test for ferritin levels
A doctor recommends a ferritin test to measure ferritin levels in the blood.
Serum Ferritin Level –The normal range for ferritin levels for men is 24 to 336 micrograms per litre, and for women is 11 to 307 micrograms per litre.
Commonly used methods to detect ferritin levels in laboratories include electrochemiluminescence (ECLIA), immunoturbidimetric method, Chemiluminescence Immunoassay (CLIA), Enzyme-Linked Immunosorbent Assay (ELISA) and Radioimmunoassay (RIA).
The detection of Ferritin using the most advanced Chemiluminescence Immunoassay quantitatively measures Ferritin levels in human serum/plasma samples, aiding in monitoring the recurrence and metastasis of malignant tumours.
Conclusion Doctors rely heavily on a ferritin test to check iron reserves in the human body . High ferritin levels indicate underlying inflammation. On the flip side, low levels mean your iron stores are depleted, signalling a deficiency. Ultimately, checking these levels through a quick blood test is the most practical, dependable, and widely trusted method to see exactly where your iron status stands.
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