Advantage Typhi IgM & IgG Card

Test Kit Type: Typhoid Test Kit (Rapid)
Result Time: Within 20 Minutes
Long Shelf Life: 30 Months at 2-30° C
Convenient Pack Size: 50 Tests

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Intended Use

Advantage Typhi IgM & IgG Card is a rapid solid phase immuno-chromatographic test for the qualitative differential and simultaneous detection of salmonella typhi (S. typhi) IgM and IgG antibodies in human serum / plasma. This test is for in vitro diagnostic use only and is intended as an aid in the earlier diagnosis of typhoid infection and in the determination of recent and past infection.

Salient Features

  • Rapid qualitative test for differential detection of Salmonella typhi (S.typhi) IgM and IgG Antibodies in Human Serum / Plasma
  • Determination of both recent and past infection
  • Results within 20 minutes
  • Bio-hazard free, fully covered, see-through Device
  • Simple & Easy to use Test Procedure
  • No Instruments required
  • Long Shelf Life: 30 months at 2-30ºC
  • Convenient Pack size: 50 Tests


Advantage Typhi IgM & IgG Card is a lateral flow immunochromatographic assay. The test uses anti-human IgM antibody (test line M) and anti-human IgG (test line G) immobilised on a nitrocellulose strip. The conjugate contains colloidal gold conjugated to S. typhi antigen. When a specimen followed by assay buffer is added to the sample well S. Typhi specific IgM &/or IgG antibodies if present, will bind to S. Typhi antigen gold conjugate making antigen antibodies complex. This complex migrates through nitrocellulose membrane by capillary action. When the complex meets the line of the corresponding immobilized antibody (anti-human IgM &/or anti-human IgG) the complex is trapped forming a purplish pink band which confirm a reactive test result.

Absence of a coloured band in the test region indicates a non reactive test result. A red procedural control line should always develop in the test device window to indicate that the test has been performed properly.

Ordering Information

Product Name Pack Size Catalog No.
Advantage Typhi IgM & IgG Card 50 Tests IR071050

Performance Characteristics

The kit has been evaluated in-house with the known panel of fresh as well as frozen S. typhi IgM & IgG antibody positive and negative samples and results are compared with licensced commercially available test. The samples included cross-reacting samples; HIV, HCV, HBV, Dengue, Chikungunya, Leptospira RA, ASO &,CRP. Following is the in-house evaluation:

Sample Type No. Of Samples tested Result of Licenced test Advantage Typhi IgM & IgG Card Results
S. typhi Antibody Negative 200 200 200
S. typhi Antibody Negative 10 10 10

Sensitivity : 100% Specificity : 100%

Precision: Within run (Intra assay) & between run (Interassay) precision have been determined by testing 10 replicates of four samples – two negative, two weak typhi IgM and/or IgG positive samples. The C.V. (%) of all the four samples were within 15%.

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